Oscillatory cerebral blood flow in postural tachycardia syndrome (1183.7)

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Altered oscillatory cerebral blood flow velocity and autoregulation in postural tachycardia syndrome

Decreased upright cerebral blood flow (CBF) with hyperpnea and hypocapnia is seen in a minority of patients with postural tachycardia syndrome (POTS). More often, CBF is not decreased despite upright neurocognitive dysfunction. This may result from time-dependent changes in CBF. We hypothesized that increased oscillations in CBF occurs in POTS (N = 12) compared to healthy controls (N = 9), and ...

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Decreased Upright Cerebral Blood Flow and Cerebral Autoregulation in Normocapnic 1 Postural Tachycardia Syndrome

22 The postural tachycardia syndrome (POTS), a chronic form of orthostatic intolerance, has 23 signs and symptoms of lightheadedness, loss of vision, headache, fatigue, and neurocognitive 24 deficits consistent with reductions in cerebrovascular perfusion. We hypothesized that young, 25 normocapnic POTS patients exhibit abnormal cerebral autoregulation (CA) that results in 26 decreased static a...

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Decreased upright cerebral blood flow and cerebral autoregulation in normocapnic postural tachycardia syndrome.

Postural tachycardia syndrome (POTS), a chronic form of orthostatic intolerance, has signs and symptoms of lightheadedness, loss of vision, headache, fatigue, and neurocognitive deficits consistent with reductions in cerebrovascular perfusion. We hypothesized that young, normocapnic POTS patients exhibit abnormal cerebral autoregulation (CA) that results in decreased static and dynamic cerebral...

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Oscillatory cerebral blood flow is associated with impaired neurocognition and functional hyperemia in postural tachycardia syndrome during graded tilt.

We hypothesize that upright cognitive impairment in patients with postural tachycardia syndrome (POTS) is caused by reduced cerebral blood flow (CBF). The CBF velocity (CBF(v)) measured by transcranial Doppler ultrasound decreased excessively during 70° tilt in a minority of patients with intermittent hyperpnea/hypocapnia. Incremental tilt showed no difference in mean CBF(v). But N-back memory ...

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Local vascular responses affecting blood flow in postural tachycardia syndrome.

Postural tachycardia syndrome (POTS) is defined by orthostatic intolerance associated with abnormal upright tachycardia. Some patients have defective peripheral vasoconstriction and increased calf blood flow. Others have increased peripheral arterial resistance and decreased blood flow. In 14 POTS patients (13-19 yr) evenly subdivided among low-flow POTS (LFP) and high-flow POTS (HFP) we tested...

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ژورنال

عنوان ژورنال: The FASEB Journal

سال: 2014

ISSN: 0892-6638,1530-6860

DOI: 10.1096/fasebj.28.1_supplement.1183.7